8-12 Dec 2019, Singapore
Prof. Bin Liu received her BS degree and Ph.D. degree from Nanjing University and National University of Singapore, respectively, before her postdoctoral training at the University of California, Santa Barbara. She joined the NUS in late 2005, where she is currently Professor and Department Head of Department of Chemical and Biomolecular Engineering. For her research focusing on organic nanomaterials for biomedical and energy applications, Prof. Liu has received many highly prestigious awards, including Singapore President’s Young Scientist Award 2008, Asia Rising Star 2013, BASF Materials Award 2014, Materials in Society Lectureship 2015, Singapore President’s Technology Award 2016, and Asian Scientist Top 100 List in 2017. Prof. Liu was named as The World’s Most Influential Minds and the Top 1% Highly Cited Researchers in Materials Science by Thomson Reuters during 2014-2017. She is the Fellow of Singapore Academy of Engineering, Asia-Pacific Academy of Materials, and the Royal Society of Chemistry.
"Organic Nanoparticles for Sensing, Imaging and Therapy"
There is an increasing trend of using organic nanoparticles and especially light-harvesting conjugated polymer nanoparticles as active materials for sensing, imaging and therapy applications. The recent results show that conjugated polymer nanoparticles could be fabricated to have tunable sizes and emission, with over 10-fold brightness as compared to inorganic quantum dots with a similar dimension. In addition, their large absorption cross-sections have also enabled them to be used as photoacoustic contrast agents and for photothermal and photo dynamic therapy. In this talk, I will discuss different strategies to form water-dispersible conjugated polymer nanoparticles and their applications as signal reporters or signal amplifiers for chemical and biological sensing/imaging and therapy. In addition, I will also briefly introduce our recent progress in organic nanoparticles with aggregation-induced emission features as replacement for quantum dots in various applications.
1. Kai Li and Bin Liu*, Polymer-encapsulated Organic Nanoparticles for Fluorescence and Photoacoustic Imaging. Chem. Soc. Rev. 2014, 43, 6570-6597.
2. Dan Ding Kai Li, Bin Liu* and Benzhong Tang*, Bioprobes Based on AIE Fluorogens, Acc. Chem. Res., 2013, 46, 2441-2453.